Quercetin: Its Antioxidant Mechanism, Antibacterial Properties and Potential Application in Prevention and Control of Toxipathy

Molecules. 2022 Oct 3;27(19):6545. doi: 10.3390/molecules27196545.

Abstract

Quercetin, as a flavonol compound found in plants, has a variety of biological activities. It is widely present in nature and the human diet, with powerful oxidative properties and biological activities. In this review, the antioxidant mechanism and broad-spectrum antibacterial properties of quercetin are revealed; the intervention effects of quercetin on pesticide poisoning and the pathway of action are investigated; the toxic effects of main mycotoxins on the collection and the detoxification process of quercetin are summarized; whether it is able to reduce the toxicity of mycotoxins is proved; and the harmful effects of heavy metal poisoning on the collection, the prevention, and control of quercetin are evaluated. This review is expected to enrich the understanding of the properties of quercetin and promote its better application in clinical practice.

Keywords: antioxidant; quercetin; toxipathy.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Antioxidants / pharmacology
  • Humans
  • Mycotoxins*
  • Pesticides*
  • Quercetin / pharmacology
  • Quercetin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Mycotoxins
  • Pesticides
  • Quercetin

Grants and funding

This research was funded by the National Natural Science Foundation of China (Grant Nos.32273074, 31972746, 31772809, and 31872538) and through a Key Grant Project of Liaoning Provincial Department of Education (Grant No. LJKZ0632).