Concern levels of beta-lactamase-producing Gram-negative bacilli in hospital wastewater: hotspot of antimicrobial resistance in Latin-America

Diagn Microbiol Infect Dis. 2023 Jan;105(1):115819. doi: 10.1016/j.diagmicrobio.2022.115819. Epub 2022 Sep 21.

Abstract

Hospital wastewater (HWW) discharges are among the main sources of antibiotic-resistant bacteria. This study detected a high frequency of beta-lactamase-producing Gram-negative Bacilli in HWW of different geographical regions of Colombia, even in the presence of the wastewater treatment plant, highlighting the importance of regulating these environments in developing countries.

Keywords: Antimicrobial resistance; Beta-lactamases; Carbapenemases; Hospital wastewater; Multidrug-resistant.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Drug Resistance, Bacterial
  • Gram-Negative Bacteria
  • Gram-Negative Bacterial Infections* / microbiology
  • Hospitals
  • Humans
  • Microbial Sensitivity Tests
  • Wastewater
  • beta-Lactamases*

Substances

  • beta-Lactamases
  • Anti-Bacterial Agents
  • Waste Water