Dysplastic nevus part II: Dysplastic nevi: Molecular/genetic profiles and management

J Am Acad Dermatol. 2023 Jan;88(1):13-20. doi: 10.1016/j.jaad.2022.05.071. Epub 2022 Oct 14.


Dermatologists frequently see patients with clinically atypical nevi and dermatopathologists interpret histologically dysplastic nevi on a near-daily basis, but there is great variability in the definition and management of such lesions. This part of the CME review focuses on information published since the previous comprehensive review (2012), with emphasis on molecular and genetic attributes of histologically dysplastic nevi and clinical management.

Keywords: atypical nevus; controversies; dysplastic nevus; melanocytic nevus; melanocytic proliferation; melanoma; nevus; photoprotection.

Publication types

  • Review

MeSH terms

  • Dysplastic Nevus Syndrome* / genetics
  • Dysplastic Nevus Syndrome* / pathology
  • Genetic Profile
  • Humans
  • Melanoma* / genetics
  • Melanoma* / pathology
  • Nevus* / genetics
  • Nevus* / pathology
  • Skin Neoplasms* / genetics
  • Skin Neoplasms* / pathology