Secondary cutaneous diffuse large B-cell lymphoma presenting with focal vesicular lesions

Dermatol Online J. 2022 Jun 15;28(3). doi: 10.5070/D328357788.


Blister formation as a presentation of B-cell lymphoma is extremely rare; only one case has been previously reported in the literature to our knowledge. We report a patient known to have refractory systemic diffuse large B-cell lymphoma who presented with nodules with overlying vesicular lesions, which was consistent with secondary cutaneous spread of diffuse large B-cell lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Lymphoma, Large B-Cell, Diffuse* / diagnosis
  • Lymphoma, Large B-Cell, Diffuse* / pathology
  • Skin Diseases*
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / pathology