Viral Infections and Wheezing in Preschool Children

Immunol Allergy Clin North Am. 2022 Nov;42(4):727-741. doi: 10.1016/j.iac.2022.05.004. Epub 2022 Sep 24.


Wheezing is common in childhood, although only a small percentage of these children develop asthma. The child's wheezing phenotype and asthma predictive indices help predict the likelihood of a future asthma diagnosis. Viral infections are common in childhood with most wheezing episodes due to respiratory syncytial virus and rhinovirus. Many treatment options exist for wheezing children including both those who wheeze persistently and those who wheeze intermittently due to viral infections.

Keywords: Asthma; Preschool; Viral infection; Wheezing.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Asthma* / diagnosis
  • Asthma* / epidemiology
  • Asthma* / etiology
  • Child, Preschool
  • Humans
  • Respiratory Sounds / etiology
  • Respiratory Syncytial Viruses
  • Rhinovirus
  • Virus Diseases* / complications
  • Virus Diseases* / diagnosis
  • Virus Diseases* / epidemiology