Assessment of the Albuscreen microalbuminuria kit in diabetic outpatients

Med J Aust. 1987 Sep 21;147(6):285-6. doi: 10.5694/j.1326-5377.1987.tb133456.x.


Diabetic patients who have albumin excretion rates of greater than 30 micrograms/min (30 mg/L at normal urine volumes) are at increased risk of the development of diabetic nephropathy. The Albuscreen microalbuminuria kit detects albuminuria at concentrations of 30 mg/L and above by an agglutination-inhibition reaction. One hundred and ninety-five random urine samples from diabetic outpatients were assessed by Albuscreen and Albustix testing for albuminuria and the results were correlated with those of a sensitive radioimmunoassay technique. Albuscreen testing was simple, easy to use and had a sensitivity of 96%, with a specificity of 88%. Albustix testing at a detection level of 50 mg/L revealed a sensitivity of 100% and a specificity of 68% (43 samples, false-positive "trace" readings), while, at 30 mg/L, the sensitivity and specificity were 90% and 71%, respectively. Therefore, Albuscreen testing is well suited as a screening test for the presence of microalbuminuria in a diabetic outpatient setting. However, the role of Albustix in screening for microalbuminuria is less well defined, especially at the 30 mg/L level of detection, and requires further investigation.

Publication types

  • Comparative Study

MeSH terms

  • Albuminuria / urine*
  • Diabetes Mellitus / urine*
  • Evaluation Studies as Topic
  • False Negative Reactions
  • False Positive Reactions
  • Humans
  • Radioimmunoassay
  • Reagent Kits, Diagnostic*
  • Reagent Strips


  • Reagent Kits, Diagnostic
  • Reagent Strips