Reclassification of coronary artery disease risk using genetic risk score among subjects with borderline or intermediate clinical risk

Razina A Ahmed; Zhuqing Shi; Andrew S Rifkin; Jun Wei; S Lilly Zheng; Brian T Helfand; Peter J Hulick; Jonathan S H Woo; Arman Qamar; David J Davidson; Liana K Billings; Jianfeng Xu

doi:10.1016/j.ijcha.2022.101136

Reclassification of coronary artery disease risk using genetic risk score among subjects with borderline or intermediate clinical risk

Int J Cardiol Heart Vasc. 2022 Oct 13:43:101136. doi: 10.1016/j.ijcha.2022.101136. eCollection 2022 Dec.

Authors

Razina A Ahmed¹, Zhuqing Shi¹, Andrew S Rifkin¹, Jun Wei¹, S Lilly Zheng¹, Brian T Helfand^{1

2

3}, Peter J Hulick^{4

5}, Jonathan S H Woo⁵, Arman Qamar^{5

6}, David J Davidson^{5

6}, Liana K Billings⁵, Jianfeng Xu^{1

2

4

3}

Affiliations

¹ Program for Personalized Cancer Care, NorthShore University HealthSystem, Evanston, IL, USA.
² Department of Surgery, NorthShore University HealthSystem, Evanston, IL, USA.
³ University of Chicago Pritzker School of Medicine, Chicago, IL, USA.
⁴ Neaman Center for Personalized Medicine, NorthShore University HealthSystem, Evanston, IL, USA.
⁵ Department of Medicine, NorthShore University HealthSystem, Evanston, IL, USA.
⁶ Cardiovascular Institute, NorthShore University HealthSystem, Evanston, IL, USA.

No abstract available

Keywords: Coronary artery disease (CAD); Reclassification; atherosclerotic cardiovascular disease (ASCVD); genetic risk score (GRS); polygenic risk score (PRS).