Role of Transluminal Balloon Angioplasty for the Treatment of Vasospasm Due to Aneurysmal Subarachnoid Haemorrhage: A Multicentric Indian Experience

Sibasankar Dalai; Uday S Limaye; Mohan V Sumedha Maturu; Satya Rao Kolli; Rajesh Pati; Madhusudhana Babu Marthati; Sailesh Modi; Aravind Varma Datla; Sameera Anantamakula; Rajasekhar Donkada

doi:10.7759/cureus.29311

Role of Transluminal Balloon Angioplasty for the Treatment of Vasospasm Due to Aneurysmal Subarachnoid Haemorrhage: A Multicentric Indian Experience

Cureus. 2022 Sep 19;14(9):e29311. doi: 10.7759/cureus.29311. eCollection 2022 Sep.

Affiliations

¹ Interventional Neuroradiology, Medicover Hospitals, Visakhapatnam, IND.
² Interventional Neuroradiology, Lilavati Hospital, Mumbai, IND.
³ Neurology, Medicover Hospitals, Visakhapatnam, IND.
⁴ Neurology, Queens NRI Hospital, Visakhapatnam, IND.
⁵ Internal Medicine, Medicover Hospitals, Visakhapatnam, IND.
⁶ Radiology, Medicover Hospitals, Visakhapatnam, IND.
⁷ Anaesthesiology, Medicover Hospitals, Visakhapatnam, IND.

Abstract

Background Aneurysmal Subarachnoid Haemorrhage (aSAH) is a complex and critical neurological condition associated with significant mortality and morbidity. Apart from the initial insult due to the aneurysmal rupture itself, re-bleeding and severe cerebral vasospasm are some of the complications of aSAH that result in overall poor outcomes. Cerebral vasospasm in post-aSAH can result in delayed ischaemic neurological deficits. In the absence of timely interventions, it can lead to grave consequences for the patient. Management of cerebral vasospasm has been evolving over the years to prevent mortality and morbidity in aSAH patients. Materials and methods During 36 months from January 2018 to December 2020, 164 patients were admitted with aSAH in multiple Indian centres. Endovascular methods were used to treat all the aneurysms. Patients were observed for clinically symptomatic cerebral vasospasm. Patients with suspected vasospasm were further evaluated with a transcranial Doppler (TCD), brain computed tomography (CT) or magnetic resonance imaging (MRI) scan. In addition, digital subtraction angiography (DSA) of cerebral vessels was performed to evaluate vasospasm further. Twenty-two patients had clinically and angiographically significant vasospasm, and 20 patients were treated with transluminal balloon angioplasty (TBA). Results Satisfactory lumen dilation was achieved in 79 out of the 91 (86.81%) vasospastic segments, namely, distal internal carotid arteries (ICAs) 100%; middle cerebral arteries (MCA) 97.56% (M1=100%, M2=100%, M3=87.5%); vertebral arteries-100%; basilar arteries-100%; anterior cerebral arteries (ACA) 67.64% (A1=75%, A2=57.14%). The mean Modified Rankin Scale (mRS) score at 90 days was 0.75. 17 patients (85%) had an overall good outcome with no new neurological deficits. There were no cases of vessel rupture, dissection or thromboembolic complications. Conclusion TBA is a valuable, safe and effective option for managing clinically significant vasospasm caused by aSAH, adjuvant to medical management.

Keywords: aneurysmal subarachnoid haemorrhage; balloon angioplasty; cerebral vasospasm; delayed ischemic neurological deficit; dsa digital subtraction angiography; endovascular angioplasty; endovascular procedures; ruptured cerebral aneurysm.