Dual Antiviral Therapy for Persistent Coronavirus Disease 2019 and Associated Organizing Pneumonia in an Immunocompromised Host

Clin Infect Dis. 2023 Mar 4;76(5):923-925. doi: 10.1093/cid/ciac847.


The management of patients with prolonged viral shedding and coronavirus disease 2019 symptoms remains unclear. Combining antivirals, as practiced in other infections, is theoretically advantageous. We present a case of persistent, symptomatic severe acute respiratory syndrome coronavirus 2 infection and associated organizing pneumonia that was successfully treated with an extended course of combination antiviral therapy.

Keywords: COVID-19; SARS-CoV-2; immunocompromise.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use
  • COVID-19*
  • Humans
  • Immunocompromised Host
  • Organizing Pneumonia*
  • SARS-CoV-2


  • Antiviral Agents