Radiomics: A review of current applications and possibilities in the assessment of tumor microenvironment

Abstract

With the recent success in the application of immunotherapy for treating various advanced cancers, the tumor microenvironment has rapidly become an important field of research. The tumor microenvironment is complex and its characteristics strongly influence disease biology and potentially responses to systemic therapy. Accurate preoperative assessment of tumor microenvironment is of great significance for the formulation of an immunotherapy strategy and evaluation of patient prognosis. As a research hotspot in medical image analysis technology, radiomics has been applied in the auxiliary diagnosis of the tumor microenvironment. This article reviews the current status of radiomics in the elective application on tumor microenvironment and discusses potential prospects.

Keywords: Radiomics; Tumor microenvironment; Tumor-associated macrophages; Tumor-infiltrating lymphocytes; Tumor-stromal ratio.