Online Geometric Calibration of a Hybrid CT System for Ultrahigh-Resolution Imaging

Tomography. 2022 Oct 12;8(5):2547-2555. doi: 10.3390/tomography8050212.


A hybrid imaging system consisting of a standard computed tomography (CT) scanner and a low-profile photon-counting detector insert in contact with the patient's body has been used to produce ultrahigh-resolution images in a limited volume in chest scans of patients. The detector insert is placed on the patient bed as needed and not attached. Thus, its position and orientation in the scanner is dependent on the patient's position and scan settings. To allow accurate image reconstruction, we devised a method of determining the relative geometry of the detector insert and the CT scanner for each scan using fiducial markers. This method uses an iterative registration algorithm to align the markers in the reconstructed volume from the detector insert to that of the concurrent CT scan. After obtaining precise geometric information of the detector insert relative to the CT scanner, the two complementary sets of images are summed together to create a detailed image with reduced artifacts.

Keywords: CT; geometric calibration; hybrid CT; image-based calibration; photon-counting detector; surface detector; tomosynthesis; ultrahigh resolution.

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Calibration
  • Humans
  • Image Processing, Computer-Assisted*
  • Phantoms, Imaging
  • Tomography Scanners, X-Ray Computed
  • Tomography, X-Ray Computed* / methods