[Ambulatory diagnosis and outpatient management of patients with hypophyseal adenomas]

Z Gesamte Inn Med. 1987 Jun 15;42(12):321-4.
[Article in German]

Abstract

In 88 patients with adenomas of the pituitary gland, among them 24 hormone-inactive tumours, 27 somatotropic adenomas and 37 prolactinomas, anamnestic data, clinical, endocrinologic and localisation-diagnostic findings as well as therapeutic measures were evaluated. Main symptoms were headache and visual disturbances. 78 of the 88 patients with adenomas of the pituitary gland were able to work at the time, when the diagnosis was made. In about 32% of the patients partial defects of the visual field were present and in 35% in the cranial computed tomogram a suprasellar and parasellar, respectively, expansion of the tumour and thus an advanced stage of the disease was established. The number of the residual findings and recidivations, respectively was great in all the three forms of the adenomas of the pituitary gland. In the prolactinomas and the somatotropic adenomas of the pituitary gland a medicamentous secondary therapy with dopamine agonists is possible. The therapy with bromocriptine reveals good results particularly in prolactinomas.

MeSH terms

  • Acromegaly / diagnosis
  • Adenoma / diagnosis*
  • Adenoma / surgery
  • Adult
  • Aged
  • Ambulatory Care
  • Female
  • Follow-Up Studies
  • Growth Hormone / metabolism
  • Humans
  • Male
  • Middle Aged
  • Pituitary Neoplasms / diagnosis*
  • Pituitary Neoplasms / surgery
  • Prolactin / metabolism

Substances

  • Prolactin
  • Growth Hormone