Economic burden in US patients with newly diagnosed acute myeloid leukemia receiving intensive induction chemotherapy

Future Oncol. 2022 Oct;18(32):3609-3621. doi: 10.2217/fon-2022-0706. Epub 2022 Oct 28.

Abstract

Aim: This retrospective, observational study assessed healthcare resource utilization (HCRU) and costs for newly diagnosed acute myeloid leukemia (AML) patients receiving intensive induction chemotherapy. Materials & methods: Adult AML patients with inpatient hospitalization or hospital-based outpatient visit receiving intensive induction chemotherapy (CPX-351 or 7 + 3 treatments) were identified from the Premier Healthcare Database (US). Results: All 642 patients had inpatient hospitalizations (median number = 2; median length of stay = 16 days); 22.4% had an ICU admission. Median total outpatient hospital cost was US$2904 per patient, inpatient hospital cost was $83,440 per patient, and ICU cost was $16,550 per patient. Discussion: In the US hospital setting, substantial HCRU and costs associated with intensive induction chemotherapy for AML were driven by inpatient hospitalizations.

Keywords: acute myeloid leukemia; costs; economic; healthcare; hospital; newly diagnosed; utilization.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Financial Stress
  • Hospitalization
  • Humans
  • Induction Chemotherapy*
  • Leukemia, Myeloid, Acute* / diagnosis
  • Leukemia, Myeloid, Acute* / drug therapy
  • Retrospective Studies

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