Updates in intraoperative strategies for enhancing intra-axial brain tumor control

Neuro Oncol. 2022 Nov 2;24(Suppl 6):S33-S41. doi: 10.1093/neuonc/noac170.


To ensure excellent postoperative clinical outcomes while preserving critical neurologic function, neurosurgeons who manage patients with intra-axial brain tumors can use intraoperative technologies and tools to achieve maximal safe resection. Neurosurgical oncology revolves around safe and optimal extent of resection, which further dictates subsequent treatment regimens and patient outcomes. Various methods can be adapted for treating both primary and secondary intra-axial brain lesions. We present a review of recent advances and published research centered on different innovative tools and techniques, including fluorescence-guided surgery, new methods of drug delivery, and minimally invasive procedural options.

Keywords: glioma; intraoperative imaging; metastatic brain tumor; minimally invasive.

Publication types

  • Review
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Brain Neoplasms* / pathology
  • Brain Neoplasms* / surgery
  • Glioma* / pathology
  • Humans
  • Neurosurgical Procedures / methods