Supportive Care in Patients with Critical Coronavirus Disease 2019

Infect Dis Clin North Am. 2022 Dec;36(4):777-789. doi: 10.1016/j.idc.2022.08.003. Epub 2022 Aug 15.


Specific therapies for the treatment of coronavirus disease 2019 (COVID-19) have limited efficacy in the event a patient worsens clinically and requires admission to the intensive care unit (ICU). Thus, providing quality supportive care is essential to the overall management of patients with critical COVID-19. Patients with respiratory failure not requiring intubation should be supported with noninvasive positive pressure ventilation, continuous positive airway pressure, or high flow oxygenation. Use of these respiratory modalities may prevent patients from subsequently requiring intubation. Basic components of supportive care for the critically ill should be applied equally to patients with COVID-19 in the ICU.

Keywords: COVID-19; Critical care; High flow nasal cannula; Lung; Noninvasive positive pressure ventilation; Prone ventilation; Supportive care.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19*
  • Critical Illness / therapy
  • Humans
  • Intensive Care Units
  • Noninvasive Ventilation*
  • Respiratory Insufficiency* / therapy