Human Immunodeficiency Virus Treatment and Prevention for Pregnant and Postpartum Women in Global Settings

Obstet Gynecol Clin North Am. 2022 Dec;49(4):693-712. doi: 10.1016/j.ogc.2022.07.002.

Abstract

Efforts to prevent mother-to-child transmission of human immunodeficiency virus (HIV) have led to dramatic reductions in pediatric HIV worldwide. New advances in HIV treatment and prevention, focused on pregnant and breastfeeding women living with HIV, have improved maternal health while decreasing vertical and horizontal HIV transmission. In this article, we describe how such interventions-including antiretroviral therapy and HIV pre-exposure prophylaxis-can be incorporated into antepartum and postpartum care in global settings.

Keywords: Antiretroviral regimens; Birth outcomes; Breastfeeding; HIV prevention; HIV treatment; Pre-exposure prophylaxis; Pregnancy.

Publication types

  • Review

MeSH terms

  • Anti-HIV Agents* / therapeutic use
  • Breast Feeding
  • Female
  • HIV
  • HIV Infections* / drug therapy
  • HIV Infections* / epidemiology
  • HIV Infections* / prevention & control
  • Humans
  • Infectious Disease Transmission, Vertical / prevention & control
  • Postpartum Period
  • Pregnancy
  • Pregnancy Complications, Infectious* / drug therapy
  • Pregnancy Complications, Infectious* / prevention & control

Substances

  • Anti-HIV Agents