Kundalini Yoga Intervention Increases Hippocampal Volume in Older Adults: A Pilot Randomized Controlled Trial

Int J Yoga. 2022 May-Aug;15(2):158-162. doi: 10.4103/ijoy.ijoy_25_22. Epub 2022 Sep 5.

Abstract

Background: Among a rapidly aging population, there is increased need for neuroprotective interventions promoting healthy neurological aging. Mind-body interventions, such as Kundalini yoga, are actively being explored as accessible means to encourage healthy aging. However, little remains known about the neurobiological effects of Kundalini yoga.

Aims: This pilot randomized-controlled trial (RCT) examined the potential neuroprotective effects of Kundalini yoga in older adults.

Methods: We conducted an RCT with 11 healthy meditation-naïve older adults. Participants were randomized to a Kundalini yoga or psychoeducation intervention. Structural magnetic resonance imaging data were obtained at baseline and 12-week follow-up. The primary outcome measure was gray matter volume of the bilateral hippocampi and bilateral posterior cingulate cortex.

Results: We found significant right hippocampal volume increases specific to the Kundalini yoga group (P = 0.034, ηp 2 = 0.408).

Conclusions: These findings provide initial neurobiological support for the neuroprotective effects of Kundalini yoga.

Keywords: Gray matter volume; Kundalini yoga; mind-body intervention; neuroimaging; neurological aging.