Status and prospects of genome-wide association studies in cotton

Muhammad Yasir; Hafiza Hamrah Kanwal; Quaid Hussain; Muhammad Waheed Riaz; Muhammad Sajjad; Junkang Rong; Yurong Jiang

doi:10.3389/fpls.2022.1019347

Status and prospects of genome-wide association studies in cotton

Front Plant Sci. 2022 Oct 18:13:1019347. doi: 10.3389/fpls.2022.1019347. eCollection 2022.

Authors

Muhammad Yasir¹, Hafiza Hamrah Kanwal², Quaid Hussain³, Muhammad Waheed Riaz³, Muhammad Sajjad³, Junkang Rong¹, Yurong Jiang¹

Affiliations

¹ The Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, College of Advanced Agricultural Sciences, Zhejiang A&F University, Hangzhou, China.
² School of Computer Science, Chongqing University of Posts and Telecommunications, Chongqing, China.
³ State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou, China.

Abstract

Over the last two decades, the use of high-density SNP arrays and DNA sequencing have allowed scientists to uncover the majority of the genotypic space for various crops, including cotton. Genome-wide association study (GWAS) links the dots between a phenotype and its underlying genetics across the genomes of populations. It was first developed and applied in the field of human disease genetics. Many areas of crop research have incorporated GWAS in plants and considerable literature has been published in the recent decade. Here we will provide a comprehensive review of GWAS studies in cotton crop, which includes case studies on biotic resistance, abiotic tolerance, fiber yield and quality traits, current status, prospects, bottlenecks of GWAS and finally, thought-provoking question. This review will serve as a catalog of GWAS in cotton and suggest new frontiers of the cotton crop to be studied with this important tool.

Keywords: GWAS; SNP; cotton; fiber; linkage disequilibrium.

Publication types

Review