Technological advances in the production of carotenoids and their applications- A critical review

Bioresour Technol. 2023 Jan;367:128215. doi: 10.1016/j.biortech.2022.128215. Epub 2022 Nov 1.


Carotenoids are naturally occurring pigments that are widely distributed in algae, fungi, bacteria, and plants. Carotenoids play a significant role in the food, feed, cosmetic, nutraceutical, and pharmaceutical industries. These pigments are effectively considered as a health-promoting compounds, which are widely used in our daily diet to reduce the risk of chronic diseases such as cardiovascular diseases, cancer, acute lung injury, cataracts, neural disorders, etc. In this context, this review paper demonstrates the synthesis of carotenoids and their potential application in the food and pharmaceutical industries. However, the demand for carotenoid production is increasing overtime, and the extraction and production are expensive and technically challenging. The recent developments in carotenoid biosynthesis, and key challenges, bottlenecks, and future perspectives were also discussed to enhance the circular bioeconomy.

Keywords: Astaxanthin; Carotenoid biosynthesis; Carotenoids; Circular bioeconomy; Extraction methods.

Publication types

  • Review

MeSH terms

  • Bacteria
  • Carotenoids*
  • Dietary Supplements
  • Fungi*
  • Plants


  • Carotenoids