Experimental transmission of Tahyna virus (California group) to wild rabbits (Oryctolagus cuniculus) by mosquitoes

Folia Parasitol (Praha). 1979;26(1):61-4.

Abstract

Two wild rabbits (Oryctolagus cuniculus) were subcutaneously infected with a dose of 2.6 dex. i.c. LD50/0.02 ml of extraneurally passaged Tahyna virus strain "236". During the 24-72 hours interval p.i. viremia was demonstrated in both animals ranging from 1.0 to 3.42 dex. i.e. LD50/0.02. Mosquitoes Aedes vexans, which had fed on them, transmitted the virus to one of three other rabbits. During 24-96 hours interval after terminated feeding of infectious mosquitoes viremia was detected in this animal ranging from 0.49 to 4.08 dex i.c. LD50/0.02 ml. Seroconversion was revealed by means of plaque reduction neutralization test 11 days after infection.

MeSH terms

  • Animals
  • Antibodies, Viral / analysis
  • Culicidae*
  • Encephalitis Virus, California / immunology
  • Encephalitis Virus, California / isolation & purification
  • Encephalitis, Arbovirus / transmission*
  • Encephalitis, California / immunology
  • Encephalitis, California / microbiology
  • Encephalitis, California / transmission*
  • Female
  • Insect Vectors*
  • Male
  • Rabbits

Substances

  • Antibodies, Viral