Autosampler for portable capillary electrophoresis

Martin Růžička; Mihkel Kaljurand; Jelena Gorbatšova; Jekaterina Mazina-Šinkar

doi:10.1016/j.chroma.2022.463619

Autosampler for portable capillary electrophoresis

J Chromatogr A. 2022 Dec 6:1685:463619. doi: 10.1016/j.chroma.2022.463619. Epub 2022 Oct 29.

Authors

Martin Růžička¹, Mihkel Kaljurand², Jelena Gorbatšova¹, Jekaterina Mazina-Šinkar¹

Affiliations

¹ Department of Chemistry and Biotechnology, School of Science, Tallinn University of Technology, Tallinn 12618, Estonia.
² Department of Chemistry and Biotechnology, School of Science, Tallinn University of Technology, Tallinn 12618, Estonia. Electronic address: mihkel@chemnet.ee.

PMID: 36334566
DOI: 10.1016/j.chroma.2022.463619

Abstract

A compact, inexpensive sampler instrument for portable capillary electrophoresis was developed for monitoring illegal drugs in human body fluids and evaluated for γ-hydroxybutyric acid (GHB) in simulated saliva samples. The sampler uses peristaltic pumps and pinch and check valves to activate liquid flows. This short communication addresses aspects of CE associated with portability, open access instrumentation, and prospects of CE for citizen science. The extensive use of items provided by the electronic and computer industry contributes to this trend.

Keywords: Capillary electrophoresis; GHB monitoring; Robust instrumentation.

MeSH terms

Body Fluids*
Electrophoresis, Capillary / methods
Humans
Illicit Drugs*

Substances

Illicit Drugs