Spironolactone: disposition, metabolism, pharmacodynamics, and bioavailability

Drug Metab Rev. 1978;8(1):151-88. doi: 10.3109/03602537808993782.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Availability
  • Biotransformation
  • Canrenoic Acid / metabolism
  • Drug Combinations
  • Erythrocytes / metabolism
  • Food
  • Half-Life
  • Humans
  • Hydrochlorothiazide / metabolism
  • Kinetics
  • Milk, Human / metabolism
  • Protein Binding
  • Species Specificity
  • Spironolactone / administration & dosage
  • Spironolactone / metabolism*
  • Tissue Distribution

Substances

  • Drug Combinations
  • Hydrochlorothiazide
  • Spironolactone
  • Canrenoic Acid