Presumption of insensibility during general anaesthesia

Br J Anaesth. 2023 Feb;130(2):e209-e212. doi: 10.1016/j.bja.2022.09.010. Epub 2022 Nov 4.

Abstract

Whilst the general presumption of the public is that general anaesthesia prevents awareness of any sensory stimuli, Lennertz and colleagues have shown in this issue of the British Journal of Anaesthesia that 11% of young adults were able to respond to auditory commands when neuromuscular blocking drugs were prevented from reaching one arm using the isolated forearm technique. This occurred with anaesthetic regimens that followed usual clinical practice in each of the 10 countries that enrolled patients, and it was significantly more common in women than in men. This high incidence demands attention. Further characterisation of the experience of these patients is essential to our understanding of the state of general anaesthesia.

Keywords: accidental awareness during anaesthesia; cognitive–motor dissociation; consciousness; general anaesthesia; isolated forearm technique; qualia.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Anesthesia, General / adverse effects
  • Anesthesia, General / methods
  • Anesthetics*
  • Female
  • Forearm
  • Humans
  • Male
  • Neuromuscular Blockade*
  • Upper Extremity
  • Young Adult

Substances

  • Anesthetics