[Retracted] Effects of nutrients on matrix metalloproteinases in human T‑lymphotropic virus type 1 positive and negative malignant T‑lymphocytes

Int J Oncol. 2023 Jan;62(1):3. doi: 10.3892/ijo.2022.5451. Epub 2022 Nov 11.


Subsequently to the publication of the above article, a concerned reader drew to the attention of the Editorial Office and the authors that certain pairings of the GAPDH western blotting control bands in Fig. 4 appeared to be strikingly similar to adjacent pairings of bands within the same gel slices; moreover, data bands featured in the HuT‑2, C91‑PL and Jurkat zymography blots in Fig. 5 also appeared to be remarkably similar, both comparing the bands within a given gel slice (as in the case of the Jurkat cell experiment in Fig. 5) or comparing between gel slices (as in the case of the Hut‑2 cells compared with the C910PL cells in Fig. 5). The Editorial Office independently investigated these concerns, and reached the conclusion that the bands did appear strikingly similar; too similar for the appearance of the bands within these figures to have arisen by chance. Moreover, the application of a software analysis program revealed that certain of the data in Fig. 6 had also appeared in another paper published by several of the same authors in another journal at around the same time. As a result of this investigation, the Editor of International Journal of Oncology has decided that this paper should be retracted from the journal on account of a lack of confidence in the authenticity of the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Oncology 45: 2159‑2166, 2014; DOI: 10.3892/ijo.2014.2638].

Keywords: acute T-cell leukemia; ascorbic acid; epigallocatechin-3-gallate; human T-cell lymphotropic virus type I; matrix metalloproteinase-2; specific nutrient synergy.

Publication types

  • Retraction of Publication