A gut-retching discovery

Cell. 2022 Nov 10;185(23):4249-4251. doi: 10.1016/j.cell.2022.10.015.


In this issue of Cell, Xie et al. identify a gut-to-brain pathway that triggers retching after toxic food ingestion or emetic agent administration. Their results shed light on how peripheral signals reach the brain to orchestrate appropriate behavioral responses and facilitate learning to prevent repeated ingestion of harmful substances.

Publication types

  • Comment

MeSH terms

  • Humans
  • Intestines*
  • Vomiting* / prevention & control