Endoscopic Submucosal Dissection in the Stomach and Duodenum: Techniques, Indications, and Outcomes

Sarah S Al Ghamdi; Saowanee Ngamruengphong

doi:10.1016/j.giec.2022.07.005

Endoscopic Submucosal Dissection in the Stomach and Duodenum: Techniques, Indications, and Outcomes

Gastrointest Endosc Clin N Am. 2023 Jan;33(1):67-81. doi: 10.1016/j.giec.2022.07.005.

Authors

Sarah S Al Ghamdi¹, Saowanee Ngamruengphong²

Affiliations

¹ Division of Gastroenterology and Hepatology, Department of Medicine, King Abdulaziz University, Jeddah, PO Box 80215, Saudi Arabia.
² Division of Gastroenterology and Hepatology, Department of Medicine, King Abdulaziz University, Building 10, 2nd Floor, PO Box 80215, Jeddah 21589, Saudi Arabia. Electronic address: sngamru1@jhmi.edu.

PMID: 36375887
DOI: 10.1016/j.giec.2022.07.005

Abstract

Gastric endoscopic submucosal dissection (ESD) is established for management of early gastric cancer (EGC). Diagnosis of EGC relies on adequate endoscopic assessment involving lesion size, histopathology, presence of ulceration, and depth of invasion. Absolute indications for endoscopic resection of EGC are if patients are presumed to have a less than 1% risk of lymph node metasta endoscopic submucosal dissectionsis, and long-term outcomes are similar to those with surgical gastrectomy. Duodenal ESD is more technically difficult and requires expertise in ESD in other locations.

Keywords: Duodenum; Dysplasia; Early gastric cancer; Endoscopic resection; Endoscopic submucosal dissection; Stomach.

Publication types

Review

MeSH terms

Duodenum / pathology
Endoscopic Mucosal Resection* / methods
Gastrectomy / methods
Gastric Mucosa / surgery
Humans
Lymphatic Metastasis / pathology
Retrospective Studies
Stomach Neoplasms* / surgery
Treatment Outcome