A review of cannabis allergy in the early days of legalization

Ann Allergy Asthma Immunol. 2023 Mar;130(3):288-295. doi: 10.1016/j.anai.2022.10.016. Epub 2022 Oct 27.


Cannabis allergy is a burgeoning field; consequently, research is still in its infancy and allergists' knowledge surrounding this topic is limited. As cannabis legalization expands across the world, it is anticipated that there will be an increase in cannabis use. Thus, we hypothesize that a concomitant rise in the incidence of allergy to this plant can be expected. Initiatives aimed at properly educating health care professionals are therefore necessary. This review presents the most up-to-date information on a broad range of topics related to cannabis allergy. Although the clinical features of cannabis allergy are becoming more well described and recognized, the tools available to make a correct diagnosis are meager and often poorly accessible. In addition, research on cannabis allergy is still taking its first steps, and new and potentially groundbreaking findings in this field are expected to occur in the next few years. Finally, although therapeutic approaches are being developed, patient and physician education regarding cannabis allergy is certainly needed.

Publication types

  • Review

MeSH terms

  • Cannabis*
  • Health Personnel
  • Humans
  • Hypersensitivity*
  • Physicians*