Non-tuberculous mycobacterial infections in geriatric patients-A neglected and emerging problem

Indian J Tuberc. 2022:69 Suppl 2:S235-S240. doi: 10.1016/j.ijtb.2022.10.010. Epub 2022 Oct 30.

Abstract

The diseases caused by Non-tuberculous mycobacteria (NTM) has increased steadily in the last two decades. Increase in incidence of NTM infections are being reported in elderly people as they are more susceptible and often experiencing high morbidity. There is prediction that NTM infections will further rise because of expected increase in elderly population by 2050. Given the importance of NTM infection in the elderly, the interest in studying NTM characteristics in the aged population is increasing. In this review, we summarize the characteristics of NTM infection among elderly patients. We focus on epidemiology, clinical presentation, and treatment options of NTM in this age group. We highlight the differences in the diagnosis and treatment between rapid and slow growing mycobacterial infections. The current recommendations for treatment of NTM have been discussed. Finally, we have reviewed the prognosis of NTM disease in elderly patients.

Keywords: Geriatrics; Liquid meida LJ media; MGIT960; Non-tuberculous mycobacterial; Solid media.

Publication types

  • Review

MeSH terms

  • Aged
  • Humans
  • Incidence
  • Mycobacterium Infections, Nontuberculous* / diagnosis
  • Mycobacterium Infections, Nontuberculous* / drug therapy
  • Mycobacterium Infections, Nontuberculous* / epidemiology
  • Mycobacterium*
  • Nontuberculous Mycobacteria
  • Prognosis