Trigeminal Neuralgia: Diagnosis and Treatment

Neurol Clin. 2023 Feb;41(1):107-121. doi: 10.1016/j.ncl.2022.09.001.


Trigeminal neuralgia is characterized classically by recurrent, evocable, unilateral brief, electric, shocklike pains with an abrupt onset and cessation that affects one or more divisions of the trigeminal nerve. In recent years, the classification of trigeminal neuralgia has been updated based on further understanding. In this manuscript, the authors aim to explain the current understanding of the pathophysiology of trigeminal neuralgia, current diagnosis criteria, and the pharmacologic management and surgical treatments of options currently available.

Keywords: Facial pain; Neuropathic pain; Pharmacologic management; Surgical treatment; Trigeminal nerve; Trigeminal neuralgia.

Publication types

  • Review

MeSH terms

  • Humans
  • Trigeminal Neuralgia* / drug therapy
  • Trigeminal Neuralgia* / therapy