Background: Coronary sinus is the target of an increasing number of percutaneous interventional procedures. Thus, in some patients, conventional cardiac resynchronization therapy (CRT) may not be feasible or preferable, and 'alternative' CRT approaches should be applied.
Case summary: We present the case of a successful CRT via direct left bundle branch permanent pacing (LBBP) in a patient with relative contraindication to conventional CRT because of previous percutaneous indirect mitral annuloplasty.
Discussion: LBBP is emerging as a promising technique for physiological cardiac pacing and CRT. It may represent the technique of choice when coronary sinus is not viable for the implant of a conventional left ventricular catheter.
Keywords: Cardiac resynchronization therapy; Case report; Conduction system pacing; Left bundle branch pacing; Percutaneous indirect mitral annuloplasty.
© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.