Valve-in-Mitral Annular Calcification Transcatheter Mitral Valve Replacement After Thrombosis of Extracardiac Valved Conduit

JACC Case Rep. 2022 Oct 5;4(19):1267-1273. doi: 10.1016/j.jaccas.2022.07.024.


We report a patient with severe mitral annular calcification, mitral stenosis/regurgitation, hypertrophic obstructive cardiomyopathy, and subaortic membrane treated with valved left atrium-left ventricle conduit, septal myectomy, and membrane resection. Subsequent thrombosis of the conduit prompted successful valve-in- mitral annular calcification transcatheter mitral valve replacement and laceration of the anterior mitral leaflet to prevent outflow obstruction. (Level of Difficulty: Advanced.).

Keywords: INR, international normalized ratio; LAMPOON, laceration of the anterior mitral leaflet to prevent outflow obstruction; LVOT, left ventricular outflow tract; MAC, mitral annular calcification; TMVR, transcatheter mitral valve replacement; computed tomography; echocardiography; hemodynamics; mitral valve; pulmonary hypertension; valve replacement.

Publication types

  • Case Reports