Adnexal and Sebaceous Carcinomas

Dermatol Clin. 2023 Jan;41(1):117-132. doi: 10.1016/j.det.2022.07.010. Epub 2022 Oct 28.

Abstract

Adnexal carcinomas and sebaceous neoplasms are rare malignant neoplasms that are derived from eccrine and apocrine sweat glands or the pilosebaceous unit. Distinction of these neoplasms is essential, as treatment, workup, and prognosis varies widely among subtypes. For this comprehensive review, apocrine, eccrine, follicular, and sebaceous neoplasms are discussed. For each neoplasm, a review of clinical presentation, classic histologic findings, and management recommendations is provided.

Keywords: Adnexal; Apocrine; Carcinoma; Eccrine; Mohs micrographic surgery; Sebaceous; Skin cancer.

Publication types

  • Review

MeSH terms

  • Adenoma*
  • Basal Cell Carcinoma*
  • Humans
  • Sebaceous Gland Neoplasms* / diagnosis
  • Sebaceous Gland Neoplasms* / therapy
  • Skin / pathology
  • Skin Neoplasms* / pathology