Kidney Transplantation From a Diabetic Donor to a Nondiabetic Recipient: A Case Report

Transplant Proc. 2022 Dec;54(10):2748-2753. doi: 10.1016/j.transproceed.2022.09.024. Epub 2022 Nov 22.


We performed a deceased-donor kidney transplantation on a 64-year-old woman. The donor was a 57-year-old man with a history of diabetes mellitus. A kidney biopsy showed nodular sclerosis, Tervaert class 3 diabetic nephropathy. Six months after surgery, serum creatinine had dropped to 1.1 mg/dL and urinary protein decreased to 0.21 g/day. A second renal biopsy showed class 3 diabetic nephropathy. This case suggests that renal tissue damage caused by a long history of diabetes mellitus does not necessarily contribute to proteinuria but is rather the result of metabolic factors including hyperglycemia and hemodynamic factors including fluid overload.

Publication types

  • Case Reports

MeSH terms

  • Diabetes Mellitus*
  • Diabetic Nephropathies* / etiology
  • Female
  • Humans
  • Kidney
  • Kidney Failure, Chronic* / surgery
  • Kidney Transplantation* / adverse effects
  • Male
  • Middle Aged
  • Proteinuria / complications