Dataset of middle cerebral artery blood flow stability in response to high-definition transcranial electrical stimulation

Data Brief. 2022 Sep 15:45:108603. doi: 10.1016/j.dib.2022.108603. eCollection 2022 Dec.

Abstract

This supplementary dataset is supportive of the randomized sham-controlled, double-blind, crossover clinical trial investigating polarity- and intensity-dependent effects of high-definition transcranial electrical stimulation (HD-tDCS) applied over the right temporo-parietal junction on mean middle cerebral artery blood flow velocity (MCA-BFv) bilaterally. Data of eleven healthy right-handed adults (6 women, 5 men; mean age 31 ± 5.6 years old) were analyzed for MCA-BFv, assessed using transcranial doppler ultrasound on the stimulated and the contralateral hemisphere concomitantly, during and after 3 blocks of 2 min HD-tDCS at 1, 2, and 3 mA. Participants received three electrical stimulation conditions (anode center, cathode center, and sham) randomly ordered across different days. The collected data is publicly available at Mendeley Data. This article and the data will inform future related investigations and safety analysis of transcranial non-invasive brain stimulation.

Keywords: HD-tDCS, high-definition transcranial direct current stimulation; Hemodynamic response; High-definition transcranial electric stimulation; MCA-BFv, middle cerebral artery blood flow velocity; Safety; TCD, transcranial doppler ultrasound; TPJ, temporo-parietal junction; Transcranial doppler.