Surgery without postoperative antibiotic treatment in diabetic foot osteomyelitis is not associated with recurrence or limb loss

Diabetes Res Clin Pract. 2022 Dec;194:110177. doi: 10.1016/j.diabres.2022.110177. Epub 2022 Nov 24.


Not using antibiotics after surgical treatment of diabetic foot osteomyelitis was not associated with failure of the surgery, recurrences, or limb loss. Antibiotics were given in doubtful complicated cases such as severe infections, cases with necrosis, foul-smelling lesions and patients requiring revascularization.

Keywords: Diabetic foot infection; Diabetic foot osteomyelitis; Postoperative antibiotics; Surgery.

MeSH terms

  • Amputation, Surgical
  • Anti-Bacterial Agents / therapeutic use
  • Debridement
  • Diabetes Mellitus* / drug therapy
  • Diabetic Foot* / complications
  • Diabetic Foot* / drug therapy
  • Diabetic Foot* / surgery
  • Humans
  • Osteomyelitis* / complications
  • Osteomyelitis* / drug therapy
  • Osteomyelitis* / surgery
  • Wound Healing


  • Anti-Bacterial Agents