Hybrid approach for harmony transcatheter pulmonary valve replacement

Catheter Cardiovasc Interv. 2023 Jan;101(1):135-139. doi: 10.1002/ccd.30504. Epub 2022 Nov 26.


The Harmony™ Transcatheter Pulmonary Valve (Medtronic) was recently approved by the Food and Drug Administration for transcatheter pulmonary valve replacement in native right ventricular outflow tracts. Despite this milestone, some patients have main pulmonary arteries that are severely dilated and continue to require surgical pulmonary valve replacement. The hybrid approach combines surgical creation of a landing zone, transcatheter valve deployment, and suture stabilization of the implanted valve. In this case series, we report the first use of a hybrid approach for Harmony™ transcatheter pulmonary valve replacement. Two cases are reported with varying approaches for surgical creation of a landing zone followed by successful placement of a Harmony™ valve.

Keywords: congenital heart disease; pediatrics; percutaneous intervention; pulmonary valve disease (PVD); transcatheter valve implantation (TVI).

Publication types

  • Case Reports

MeSH terms

  • Cardiac Catheterization
  • Heart Valve Prosthesis Implantation* / adverse effects
  • Heart Valve Prosthesis*
  • Humans
  • Prosthesis Design
  • Pulmonary Valve Insufficiency* / diagnostic imaging
  • Pulmonary Valve Insufficiency* / surgery
  • Pulmonary Valve* / diagnostic imaging
  • Pulmonary Valve* / surgery
  • Treatment Outcome