The Spectrum of Infections in Patients with Lung Cancer

Cancer Invest. 2023 Jan;41(1):25-42. doi: 10.1080/07357907.2022.2153860. Epub 2022 Dec 20.


Although diagnostic and therapeutic advances in lung cancer (LC) have increased the survival of patients, infection and its complications are still among the most important causes of mortality. The disruption of tissue caused by tumor mass, management of cancer therapy and alteration in the humoral/cellular immune systems due to both cancer itself and therapy considerably increase susceptibility to infection in cancer patients. Particularly, opportunistic microorganisms should be considered, then applying rapid and sensitive diagnostic methods for them. Thus, cancer patients who are already exposed to difficult, long-term and expensive treatments can be prevented from dying from complications related to infections.

Keywords: Lung cancer; bacteria; fungus; opportunistic infections; parasite; virus.

MeSH terms

  • Humans
  • Lung Neoplasms* / complications
  • Lung Neoplasms* / therapy