Obesity - a still underestimated risk factor during antenatal corticosteroids therapy

Ginekol Pol. 2022 Nov 30. doi: 10.5603/GP.a2022.0132. Online ahead of print.


Pregnant obese patients are at a greater risk of developing gestational diabetes (GDM). We present a case of an obese patient who developed GDM G2 and periventricular leukomalacia in the neonate after antenatal corticosteroids (ACS) treatment. We suggest that routine blood glucose monitoring should be considered during a course of prenatal steroid therapy in all patients in a higher risk group for glucose intolerance. In cases of hyperglycemia, intensive insulin therapy should be advised. More research and new recommendations are needed on antenatal glucocorticoids (GCS), obesity, and GDM.

Keywords: corticosteroids; gestational diabetes mellitus; insulin therapy; obesity; pregnancy.