1 Department of Anesthesia, Critical Care and Pain Medicine; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: mbottiro@bidmc.harvard.edu.
2 Department of Medicine and Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.
3 Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Department of Anesthesia, Intensive Care and Pain Therapy, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.