Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion

Expert Rev Clin Pharmacol. 2023 Feb;16(2):93-95. doi: 10.1080/17512433.2023.2154652. Epub 2022 Dec 6.
No abstract available

Keywords: Breast cancer; CYP2D6; endocrine therapy; endoxifen; pharmacogenetics; pharmacokinetics; tamoxifen; therapeutic drug monitoring.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Antineoplastic Agents, Hormonal / pharmacology
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms* / drug therapy
  • Cytochrome P-450 CYP2D6 / genetics
  • Female
  • Genotype
  • Humans
  • Longitudinal Studies
  • Tamoxifen* / pharmacology
  • Tamoxifen* / therapeutic use

Substances

  • Tamoxifen
  • Antineoplastic Agents, Hormonal
  • Cytochrome P-450 CYP2D6