Hemodynamic Characterization of Neonates With Congenital Diaphragmatic Hernia-Associated Pulmonary Hypertension by Cardiac Catheterization

J Pediatr. 2023 Apr:255:230-235.e2. doi: 10.1016/j.jpeds.2022.11.028. Epub 2022 Dec 1.

Abstract

We examined the results of cardiac catheterization in infants with congenital diaphragmatic hernia (CDH) from 2009 to 2020. Catheterization confirmed pulmonary arterial hypertension in all cases (n = 17) and identified left ventricular (LV) diastolic dysfunction (LVDD) in 53%. LVDD was associated with greater respiratory morbidity. Preprocedural noninvasive assessment showed inconsistent agreement with catheterization results.

Keywords: cardiac catheterization; congenital diaphragmatic hernia; left ventricular diastolic dysfunction; neonatal; pulmonary hypertension.

Publication types

  • Case Reports

MeSH terms

  • Cardiac Catheterization
  • Hemodynamics
  • Hernias, Diaphragmatic, Congenital* / complications
  • Humans
  • Hypertension, Pulmonary* / complications
  • Infant
  • Infant, Newborn
  • Pulmonary Arterial Hypertension*
  • Retrospective Studies
  • Ventricular Dysfunction, Left* / complications