Intra-abdominal Mass, Obstructive Jaundice, and Eosinophilia

Li Wang; Guizhi Zhang; Wenjie Zheng; Xinping Tian; Mengtao Li; Xiaofeng Zeng; Fengchun Zhang

doi:10.2478/rir-2022-0015

Intra-abdominal Mass, Obstructive Jaundice, and Eosinophilia

Rheumatol Immunol Res. 2022 Jul 6;3(2):90-92. doi: 10.2478/rir-2022-0015. eCollection 2022 Jun.

Authors

Li Wang¹, Guizhi Zhang¹, Wenjie Zheng¹, Xinping Tian¹, Mengtao Li¹, Xiaofeng Zeng¹, Fengchun Zhang¹

Affiliation

¹ Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, 100730, China.

Abstract

Eosinophilic granulomatosis with polyangiitis(EGPA) is a systemic vasculitis syndrome associated with eosinophilia, which most commonly involves the lung, skin, cardiovascular, gastrointestinal, renal, and peripheral nervous systems (PNS). We report a case of a 48-year-old man presented as obstructive jaundice caused by intra-abdominal mass, and he also had elevated peripheral eosinophils. The pathological features of the mass included vasculitis and eosinophils infiltration. At first he was diagnosed as EGPA and treated by glucocorticoid and cyclophosphamide. The patient did not get complete response after six months and then the repeat biopsy proved that he had non-Hodgkin's lymphoma.

Keywords: eosinophilic granulomatosis with polyangiitis (EGPA); eosinophils; lymphoma.

Publication types

Case Reports