Marine-derived Natural Products as Anticancer Agents

Med Chem. 2023;19(6):538-555. doi: 10.2174/1573406419666221202144044.


Cancer is a deadly human disease on the rise due to changes in lifestyle, nutrition, and global warming. Cancer is characterized by uncontrolled, disordered, and undesired cell division. About 60% of cancer medicines approved by the FDA are made from natural ingredients. Intensive efforts over the last decade to better understand the vast chemical diversity provided by marine life have resulted in an intriguing "marine pipeline" of potential anticancer clinical and preclinical treatments. The molecular targets of marine products as anticancer drugs, as well as different reported compounds acting on distinct targets, are the topic of this review.

Keywords: Anticancer; anti-cancer; anti-prostate; marine compounds; marine drugs; natural.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents* / pharmacology
  • Antineoplastic Agents* / therapeutic use
  • Aquatic Organisms / chemistry
  • Biological Products* / chemistry
  • Biological Products* / pharmacology
  • Humans
  • Neoplasms* / drug therapy


  • Biological Products
  • Antineoplastic Agents