Uncoupling of energy production

Yi Shiau Ng; Doug M Turnbull

doi:10.1016/j.cmet.2022.11.008

Uncoupling of energy production

Cell Metab. 2022 Dec 6;34(12):1901-1903. doi: 10.1016/j.cmet.2022.11.008.

Authors

Yi Shiau Ng¹, Doug M Turnbull²

Affiliations

¹ Wellcome Centre for Mitochondrial Research, Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK. Electronic address: yi.ng@newcastle.ac.uk.
² Wellcome Centre for Mitochondrial Research, Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK. Electronic address: doug.turnbull@newcastle.ac.uk.

PMID: 36476932
DOI: 10.1016/j.cmet.2022.11.008

Abstract

Mitochondrial genetic diseases are a very diverse group of conditions. A recent report by Mootha and colleagues in NEJM describes the underlying genetic defect and clinical findings in monozygotic twins with uncoupling of ATP production.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Mitochondrial Diseases* / genetics
Twins, Monozygotic*

Grants and funding

WT_/Wellcome Trust/United Kingdom