Current Radiotherapy Considerations for Nasopharyngeal Carcinoma

Cancers (Basel). 2022 Nov 24;14(23):5773. doi: 10.3390/cancers14235773.


Radiotherapy is the primary treatment modality for nasopharyngeal carcinoma (NPC). Successful curative treatment requires optimal radiotherapy planning and precise beam delivery that maximizes locoregional control while minimizing treatment-related side effects. In this article, we highlight considerations in target delineation, radiation dose, and the adoption of technological advances with the aim of optimizing the benefits of radiotherapy in NPC patients.

Keywords: adaptive planning; artificial intelligence; nasopharyngeal cancer; particle therapy; radiotherapy; target delineation.

Publication types

  • Review

Grants and funding

W.T.N. and A.W.M.L. are supported by the Shenzhen Key Laboratory for cancer metastasis and personalized therapy (ZDSYS20210623091811035) and the Shenzhen Fundamental Research Program, China (CYJ20210324114404013).