Pancreatitis in Pregnancy-Comprehensive Review

Int J Environ Res Public Health. 2022 Dec 3;19(23):16179. doi: 10.3390/ijerph192316179.


Acute and chronic pancreatitis, until recently observed incidentally in pregnancy, has occurred much more frequently in the last 2-3 decades. Particularly severe complications for the mother and fetus may be a consequence of acute pancreatitis. Therefore, it is important to know more about the diagnostic and therapeutic possibilities of pancreatic diseases in the course of pregnancy. Epidemiology, causes, clinical characteristics, differential diagnosis, and complex management are presented in this review. Particular emphasis is on the prevention of acute pancreatitis (AP) through the proper diagnosis and treatment of cholelithiasis and hypertriglyceridemia, both before and during pregnancy. The most up-to-date reports and management strategies are presented. This publication contributes to a wide group of scientists and practitioners better understanding the discussed issues, and indicates the directions of research for the future.

Keywords: acute pancreatitis; cholelithiasis; chronic pancreatitis; hypertriglyceridemia; pregnancy.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Cholelithiasis*
  • Female
  • Humans
  • Hypertriglyceridemia* / complications
  • Pancreatitis* / diagnosis
  • Pancreatitis* / epidemiology
  • Pancreatitis* / therapy
  • Pregnancy
  • Pregnancy Complications* / diagnosis
  • Pregnancy Complications* / epidemiology
  • Pregnancy Complications* / therapy

Grants and funding

This research was funded by the Medical University of Lublin.