Target Trial Emulation: A Framework for Causal Inference From Observational Data

JAMA. 2022 Dec 27;328(24):2446-2447. doi: 10.1001/jama.2022.21383.
No abstract available

Plain language summary

This Guide to Statistics and Methods describes the use of target trial emulation to design an observational study so it preserves the advantages of a randomized clinical trial, points out the limitations of the method, and provides an example of its use.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Causality*
  • Comparative Effectiveness Research
  • Observational Studies as Topic*
  • Research Design*