Endoscopic injection sclerotherapy with polidocanol for cardiac varices in children and adolescents

Arch Pediatr. 2023 Feb;30(2):109-112. doi: 10.1016/j.arcped.2022.11.016. Epub 2022 Dec 9.


Background: Like esophageal varices, cardiac varices are often treated with endoscopic variceal ligation (EVL). However, we previously reported that EVL for cardiac varices may be associated with a high risk of rebleeding from the ulcer if the O-ring spontaneously drops off early. The efficacy and safety of para-variceal endoscopic injection sclerotherapy (EIS) with polidocanol for the treatment of cardiac varices in children and adolescents were evaluated.

Methods: Eleven patients under 18 years of age with portal hypertension who underwent para-variceal EIS with polidocanol for cardiac varices with red signs, which were considered to be at high risk of bleeding, were retrospectively reviewed.

Results: One session of para-variceal polidocanol-EIS was performed for each of the 11 patients. One patient experienced temporary hypoxia due to aspiration of saliva when the tracheal intubation tube was removed after the procedure but recovered by endotracheal suctioning; there were no other adverse events. In six of the eight cases in which efficacy could be evaluated, eradication of cardiac varices was achieved.

Conclusion: Para-variceal polidocanol-EIS may be considered instead of EVL for small cardiac varices with red signs in pediatric patients with cardiac varices.

Keywords: Biliary atresia; EIS; Pediatric; Polidocanol; Portal hypertension; Varices.

MeSH terms

  • Adolescent
  • Child
  • Esophageal and Gastric Varices* / etiology
  • Esophageal and Gastric Varices* / therapy
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / therapy
  • Humans
  • Ligation / adverse effects
  • Ligation / methods
  • Polidocanol
  • Recurrence
  • Retrospective Studies
  • Sclerotherapy / adverse effects
  • Sclerotherapy / methods
  • Varicose Veins* / etiology


  • Polidocanol
  • dodecylnonaoxyethylene glycol monoether