Bacterial Vaginosis: A Comprehensive Narrative on the Etiology, Clinical Features, and Management Approach

Cureus. 2022 Nov 10;14(11):e31314. doi: 10.7759/cureus.31314. eCollection 2022 Nov.

Abstract

Due to the intricate balance of the vaginal microbiota's ecology, bacterial vaginosis is documented in one-third of females globally at various times of their lives. It is a typical reason for unusual vaginal discharge and is linked to various health problems. Gardnerella vaginalis is one of the anaerobic microorganisms linked to bacterial vaginosis. bacterial vaginosis is diagnosed by Amsel's criteria as well as comparisons among Amsel's criteria, Nugent's criteria, and Hay/Ison's criteria. To scan and assess the degree of dysbiosis within the vaginal microbiome, researchers have upped their game by combining cutting-edge molecular methods, with a focus on how specific microbial populations fluctuate in comparison to a healthy condition. A clue cell can be detected on a simple wet mount of vaginal secretions. Despite receiving regular antibiotic therapy, a substantial risk of treatment failure and bacterial vaginosis recurrence persists. Researchers have revealed positive treatment effects and reduced the infection of the female reproductive system with harmful bacteria.

Keywords: amsel’s criteria; bacterial vaginosis; gardnerella; hay/ison’s criteria; lactobacillus; microbiome; nugent’s criteria; probiotics.

Publication types

  • Review