The ageing retina: physiology or pathology

Eye (Lond). 1987;1 ( Pt 2):282-95. doi: 10.1038/eye.1987.47.

Abstract

The human retina is a unique component of the nervous system in that throughout life it is continuously exposed to optical radiation between 400 and 1400 nm. The physiology of the ageing retina and the regression in visual performance with age cannot therefore be studied in isolation, or discriminated, from the life long cumulative effects of radiant exposure. This paper describes the spectrum of age related changes in the retina as they merge imperceptibly between declining visual function and overt pathology.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aging / pathology*
  • Basement Membrane / pathology
  • Child
  • Child, Preschool
  • Choroid / pathology
  • Female
  • Humans
  • Light
  • Macula Lutea / pathology
  • Macular Degeneration / pathology
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Photoreceptor Cells / ultrastructure
  • Pigment Epithelium of Eye / pathology
  • Retina / physiopathology*
  • Retina / radiation effects